Infitol
Mannitol
Short Description
Infitol Infusion is a clear solution, colorless, sterile and pyrogen-free which is available in 500 ml softbag package.
Indications
Infitol as an osmotic diuretic could be used for several different purposes, among others :
Prophylaxis of acute renal failure.
Differential diagnosis of acute oliguria.
Reduction of cerebrospinal fluid and intraocular pressure.
Specification
Infitol Infusion need to be warmed before administration to dissolve its crystal.
Adult dose to induce diuresis : Dosage range between 50-200 g with 24 hours infusion. Infusion rate is adjusted to maintain urine volume at least 30-50 ml per hours. Patients with clear oliguria or doubt about renal function, treatment should be preceded by test dose. Recommended test dose is 200 mg/kgBW (about 75 ml) for 3-5 minutes. If the dose of the first or second trial failed to induce urine flow greater than 30 ml per hour for 2-3 hours, the patient need to be reassessed.
Dose for the prevention of acute renal failure during surgery or treatment oliguria :Total dose is 50 - 100 g for adult patients.
Dose to lower intracranial pressure and brain mass before brain surgery, or lowering intraocular pressure during glaucoma episodic : A total of 1.5 - 2 kg Infitol Infusion is administered as 20% solution within 30 - 40 minutes
