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Levofloxacin Infus

Levofloxacin hemihydrates

Short Description

Levofloxacin Hemihydrate contains Levofloxacin hemihydrates (equivalent to Levofloxacin) as active ingredient is available in IV infusion 500 mg/100 ml and 750 mg/150 ml.

Indications

Levofloxacin Hemihydrate is indicated for the treatment of adults (≥18 years of age) with mild, moderate and severe infections caused by susceptible bacteria:

  • Acute bacterial sinusitis due to Streptococcus pneumoniae, Haemophilus influenzae or Moraxella catarrhalis.

  • Acute bacterial exacerbation of chronic bronchitis due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae or Moraxella catarrhalis.

  • Nosocomial pneumonia due to Methicillin-susceptible Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, or Streptococcus pneumoniae. Adjunctive therapy should be used as clinically indicated. Where Pseudomonas aeruginosa is a documented or presumtive pathogen, combination therapy with an anti-pseudomonal β-lactam is recommended.

  • Community-acquired pneumonia due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila or Mycoplasma pneumoniae.

  • Multi Drug Resistant (MDR) Streptococcus pneumoniae isolates are strains resistant to two or more of the following antibiotics: Penicillin, second generation Cephalosporin, e.g., Cefuroxime, Macrolides, Tetracyclines and Trimethoprim/Sulfamethoxazole.

  • Chronic bacterial prostatitis caused by Escherichia coli, Enterococcus faecalis, or Staphylococcus epidermidis.

  • Complicated skin and skin structure infections.

  • Complicated urinary tract infections.

  • Acute pyelonephritis.

Specification

Usual dose in patients with normal renal function : 250 mg - 750 mg once daily depends on the type and severity of the infection and the

sensitivity of the presumed causative pathogen.

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