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Dansefion

Ondansetron Hydrochloride

Short Description

DANSEFION is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.

Indications

Parenteral

Nausea and vomiting associated with cancer chemotherapy

Adult: Highly emetogenic chemotherapy: 8 mg as a single dose, given IM or slow IV inj immediately prior to treatment; or 8 mg IM or slow IV inj given immediately prior to treatment followed by either continuous IV infusion of 1 mg/hr for up to 24 hr or by a further 2 doses of 8 mg 2-4 hr apart; or 32 mg as a single dose via IV infusion over ≥15 min immediately prior to treatment; or 150 mcg/kg IV infusion over 15 min (beginning 30 min prior to chemotherapy) and repeated 4 and 8 hr after the 1st dose. Anti-emetic efficacy can be enhanced by giving dexamethasone sodium phosphate 20 mg IV prior to chemotherapy. Child: ≥6 mth 150 mcg/kg via IV infusion 30 min prior to the start of chemotherapy, repeat dose at 4 and 8 hr after the initial dose. Elderly: No dosage adjustment needed.

Treatment and prophylaxis of postoperative nausea and vomiting

Adult: 4 mg as a single dose via IM or 4-8 mg slow IV inj at induction of anaesth. Child: ≥1 mth 100 mcg/kg by slow IV inj. Max: 4 mg. Elderly: No dosage adjustment needed.

Specification

Injection

Dansefion Injection 4 mg/2 ml

  • Each ml contains : Ondansetron Hydrochloride equivalent to Ondansetron 2 mg

  • Box, 5 ampoules @ 2 ml


Oral

Dansefion Film Coated Caplet 4 mg

  • Each caplet contains : Ondansetron HCl dihydrate equivalent to Ondansetron 4 mg

  • Box, 3 strips @ 10 film coated caplets

Dansefion Film Coated Caplet 8 mg

  • Each caplet contains : Ondansetron HCl dihydrate equivalent to Ondansetron 8 mg

  • Box, 3 strips @ 10 film coated caplets

Dansefion Syrup 4 mg/5 ml

  • Each 5 ml contains : Ondansetron HCl dihydrate equivalent to Ondansetron 4 mg

  • Box, 1 bottle @ 60 ml

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Gastrointestinal & Hepatobiliary Systems Product